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Or we'll die? Pocket guide to poisons and antidotes

16. july 2017 at 11:51 | Veronika Valdova, ARETE-ZOE |  Medicine & Pharmacy
In January 2017, the Royal College of Emergency Medicine and National Poisons Information Service issued a new Guideline on Antidote Availability for Emergency Departments. Additional information can be obtained in TOXBASE and the British National Formulary (BNF). Antidotes and other medications for the treatment of poisoned patients shall be stored in a separate storage area (Royal College of Emergency Medicine, & National Poisons Information Service, 2017).

Only a few antidotes are regularly used in clinical practice to treat poisoned patients: activated charcoal, acetylcysteine, naloxone, sodium bicarbonate, atropine, flumazenil, therapeutic antibodies, and vitamins.
  • Flumazenil shall be used as a reversal of iatrogenic over-sedation with benzodiazepines;
  • Methylene blue is used to treat methemoglobinemia;
  • Naloxone reverses opioid toxicity;
  • Procyclidine is indicated for the treatment of dystonic reactions.
Sodium bicarbonate shall be used for the treatment of overdose with tricyclic antidepressants, class I a and I c antiarrhythmics and to alkalize urine (Buckley, Dawson, Juurlink, & Isbister, 2016).

 

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